MBEC Biofilm Technologies Inc. Multidisciplinary research teams find solutions to industrially relevant biofilm problems, as well as beneficial uses for microbial biofilms at the Montana State University Center for Biofilm Engineering (CBE). (1.49 MB) Nicole Kenny, Virox Technologies Inc. Excerpt:“It is interesting to note, that more than 99 per cent of all bacteria in the world exists as part of a biofilm community although, historically, microbiologists have only studied free-floating (planktonic) bacteria.” pg. 7 Rodney M. Donlan, CDC Excerpt:“Microorganisms attach to surfaces and develop biofilms.
Biofilm-associated cells can be differentiated from their suspended counterparts by generation of an extracellular polymeric substance (EPS) matrix, reduced growth rates, and the up- and down- regulation of specific genes. Attachment is a complex process regulated by diverse characteristics of the growth medium, substratum, and cell surface.
” Affinity Laboratory Technologies Excerpt:“Microorganisms attach to surfaces and develop biofilms. Biofilm-associated cells can be differentiated from their suspended counterparts by generation of an extracellular polymeric substance (EPS) matrix, reduced growth rates, and the up- and down- regulation of specific genes. Attachment is a complex process regulated by diverse characteristics of the growth medium, substratum, and cell surface. ” Agriculture and Agri-Food Canada Excerpt:“For the food industry, the world of microbes might be compared to a minuscule battlefield, where its allies and its enemies are engaged in a deadly struggle on a microscopic scale.
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Pathogens and micro-organisms that cause spoilage are particularly formidable adversaries, as they give rise to many economic problems and threats to human health. One major source of contamination is surfaces. Bacteria tend to stick tightly to surfaces, even surfaces that have been meticulously disinfected ”. Protocols/Product Use Instructions - AJIC: American Journal of Infection Control. 33(6):320-325, August 2005.
Perez, Justo PhD; Springthorpe, V. Susan MSc; Sattar, Syed A.
PhD Excerpt:“Clostridium difficile is an increasingly common nosocomial pathogen, and its spores are resistant to common environmental surface disinfectants. Many high-level disinfectants (eg, aldehydes) are unsuitable for environmental decontamination because they need several hours of contact to be sporicidal. This study tested the potential of selected oxidative microbicides to inactivate C difficile spores on hard surfaces in relatively short contact times at room temperature. ” (83 KB) Carla Feltrin RN, BA, CNCC(C), Subhash K. Patel MD, FRCPC, FCAP, Tracey Davey RN, BScN, CPHQ Ministry of Health and Long Term Care (431 KB) Infection Prevention and Control Services Vancouver Island Health Authority Canadian Centre for Occupational Health & Safety(CCOHS) Excerpt:“'Clostridium difficile (also known as C.difficile) is a bacterium associated with diarrhea and intestinal inflammation among patients or residents in health care facilities.'
” (226 KB) V. Susan Springthorpe, Justo Perez & Syed A. Sattar CSSA, Dr.
Michelle Alfa (65 KB) U.S. Environmental Protection Agency Unlike US test requirements, Canadian Sporicidal surface disinfectants are tested on a soil challenged surface to more accurately determine their efficacy in an environment more representative of reality. Soiled surfaces present the potential for inactivating certain disinfectant chemistries (ie bleach) and therefore testing with a soil load instils confidence that disinfection can be achieved, even if suboptimal cleaning occurs. Download Free Adobe After Effects Weather Templates on this page.
(301 KB) BMC Infectious Diseases September 2010: Michelle J Alfa, Evelyn Lo, Alana Wald, Christine Dueck, Pat DeGagne and Godfrey KM Harding C. Difficle spores in the environment of patients with C. Difficile associated disease (CDAD) are difficult to eliminate. Bleach (5000 ppm) has been advocated as an effective disinfectant for the environmental surfaces of patients with CDAD. Few alternatives to bleach for non-outbreak conditions have been evaluated in controlled healthcare studies.
Excerpt:“Our data indicate that the AHP formulation evaluated that has some sporicidal activity was significantly better than the currently used SHP formulation. This AHP formulation provides a one-step process that significantly lowers the C. Difficile spore level in toilets during non-outbreak conditions without the workplace safety concerns associated with 5000 ppm bleach.” (2.71 MB) AJIC Vol. 1, February 2009, pg. 9-14 Gravel D, Gardam M, Taylor G, Miller M, Simor A, McGeer A, Hutchinson J, Moore D, Kelly S, Mulvey M; Canadian Nosocomial Infection Surveillance Program.